Introduction

Alcohol 120% 2.1.1.2201 Crack Download is widely believed to be the only psychoactive substance with addictive potential “that is not controlled at the international level by legally binding regulatory frameworks” despite its profound implications for populations and public health.

1 The adverse effects of alcohol on health has been the subject of a rising number of studies in recent years,,2 1with such research asserting that even modest alcohol use contributes to over 60 acute and chronic health conditions.3 Studies have also shown that alcohol consumption is associated with more than 200 diseases, although its pathogenicity and lethality through chronic illnesses depend on the amount and quality of alcohol consumed and the patterns that underlie its intake.4

Some scholars suggested that drinking small amounts of alcohol helps prevent conditions such as diabetes, ischemic heart disease (IHD), dementia, and cognitive decline, but none of the seminal review studies reported a “safest level” of alcohol consumption.1,3 Another major concern about alcohol intake is that its health implications that occur through the mechanisms of other diseases, especially cancers, are likely to be underreported.

5 Such consumption, for instance, is associated with 18% of suicides, 18% of interpersonal conflicts and violence, 27% of road accidents, 13% of epilepsy cases, 48% of liver cirrhosis cases, 26% of oral cancer cases, 20% of tuberculosis (TB) cases, 11% of colon cancer cases, 5% of breast cancer cases, and 7% of hypertension (HTN) and heart disease cases worldwide, as indicated by the World Health Organization (WHO).6 The WHO report notably reflected the use of the term “harmful use”.6 Even though experts believe that no level of alcohol consumption improves health.1 In general, even moderate alcohol consumption considerably increases the overall risk of mortality, especially among young individuals.7

Epidemiology

Alcohol 120% 2.1.1.2201 Crack The latest WHO report showed that in 2016, about 43% of the population over the age of 15 years (2.3 billion people) had consumed alcohol in the preceding 12 months.1 The report also indicated that the lowest and highest alcohol consumption rates (2.9% and 59.9%, respectively) were found among the populations belonging to the areas where the Regional Office for the Eastern Mediterranean (EMRO) and the Regional Office for Europe have jurisdiction, respectively. The total alcohol per capita consumption (APC) in 2016 was 6.4 liters, which does not reflect any change from the levels recorded in 2010.

However, a decline and an increase in this level were observed in the European region and the Western Pacific and Southeast Asia, respectively. Nevertheless, the percentage of “current drinkers” all over the world in 2016 was generally 4.6% lower than that in 2000, mostly because of an increase in prevalence of former drinkers and much less due to increases in the proportion of people with no alcohol use in their lifetime.1

Interestingly, 25.5% of the alcohol consumed globally is ingested illicitly or without proper supervision. The alcohol consumed in this manner includes homemade alcoholic drinks, medical and industrial alcohols that are misused as drinks, and other alcoholic beverages that are produced and sold illegally.

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This type of alcohol consumption occurs in EMRO countries and in the Region of the Americas (AMR) at rates of 70.2% and 1.1% out of the total, which are respectively the highest and lowest rates worldwide.1 In 2016, the world’s average rate of heavy episodic drinking (HED) (defined as drinking 60 g or more of pure alcohol on at least a single occasion at least once per month) was 18.2%, and the highest and lowest rates were observed in European and EMRO countries with 26.4% and 0.5% of total consumption, respectively. HED is associated with alcohol poisoning and increased respiratory rate, heart rate, body temperature, and gag reflex, which may lead to a coma and death.

1 Still in 2016, alcohol use was the most important risk factor for death in the age group of 15 to 49 years and the seventh leading risk factor for all deaths and disability-adjusted life years (DALYs). In the aforementioned age group, 5.3% of all deaths in the world (2.8 million deaths), 12.2% of all deaths among men, and 3.8% of all deaths among women, are related to alcohol consumption.3 These statistics render alcohol deadlier than afflictions such as diabetes, TB and acquired immune deficiency syndrome (AIDS).1

Alcohol Drinks Although populations belonging to the lower socioeconomic class consume alcohol to a smaller extent than individuals of high economic standing, they exhibit higher morbidity and mortality rates because of the adverse effects stemming from their combination of alcohol consumption with other hazardous behaviours and conditions, such as smoking, poor diet, and obesity; lower socioeconomic groups also have a greater occurrence of HED.8

Alcohol-related harms

Alcohol Example To identify what the most harmful drug is in the world, British researchers recently conducted a multi-criteria decision analysis to rank medications in this respect.9 They found that in the United Kingdom (UK), the reputation of being the most dangerous substance in terms of overall harm to users and others belonged to alcohol.

In another study on substance abuse, a scale called the margin of exposure (MOE) [the ratio of the no observed adverse effect level (NOAEL) of a substance to the normal dose of exposure] was used to rank control measures for substance abuse and health risk assessment.10 The researchers revealed that, on a population scale, alcohol was the only substance falling within the high-risk category.10 In what follows, the latest developments in research on alcohol-related harms are discussed.

Conclusion

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